Thierry Le Diguarher

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

Patrick Casara, James Davidson, Audrey Clapéron et al. · Oncotarget · 2018 · 109 citations · Full text

Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1

James B. Murray, James Davidson, I‐Jen Chen et al. · ACS Omega · 2019 · 68 citations · Full text

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

Patrick Casara, James Davidson, Audrey Clapéron et al. · HAL (Le Centre pour la Communication Scientifique Directe) · 2018 · 47 citations

Hematological Malignancy, Tumor Biology, Oncology +14

Synthesis and physicochemical properties of oligonucleotides built with either<i>α</i>-L or<i>β</i>-L nucleotides units and covalently linked to an acridine derivative

Ulysse Asseline, Jean-François Hau, Stanislas Czernecki et al. · Nucleic Acids Research · 1991 · 37 citations · Full text

Nucleic Acid Chemistry, Bioorganic Chemistry, Engineering +12

Bax Activation by Engagement with, Then Release from, the BH3 Binding Site of Bcl-x _L

Fabien Gautier, Yannis Guillemin, Pierre‐François Cartron et al. · Molecular and Cellular Biology · 2010 · 36 citations · Full text