Chul‐Hwan Lee

Capturing the Onset of PRC2-Mediated Repressive Domain Formation

Ozgur Oksuz, Varun Narendra, Chul‐Hwan Lee et al. · Molecular Cell · 2018 · 280 citations · Full text

Signal Transduction, Molecular Regulation, Molecular Biology +2

H1 histones control the epigenetic landscape by local chromatin compaction

Michael A. Willcockson, Cary N. Weiss, Boris Bartholdy et al. · Nature · 2020 · 188 citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +9

Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma

James M. Stafford, Chul‐Hwan Lee, Philipp Voigt et al. · Science Advances · 2018 · 185 citations · Full text

Epigenetic Change, Cancer Biology, Glioma +21

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

Chul‐Hwan Lee, Jia-Ray Yu, Sunil Kumar et al. · Molecular Cell · 2018 · 134 citations · Full text

Chromatin, Chromatin Remodeling, Molecular Regulation +10

Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2

Chul‐Hwan Lee, Marlene Holder, Daniel Grau et al. · Molecular Cell · 2018 · 133 citations · Full text

Biochemistry, Natural Sciences, Molecular Biology +5