Changfeng Huang

Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

Min Qiu, Yan Tang, Jinjin Chen et al. · Proceedings of the National Academy of Sciences · 2022 · 481 citations · Full text

Pharmacy, Molecular Biology, Pharmaceutics +17

Lipid nanoparticle-mediated lymph node–targeting delivery of mRNA cancer vaccine elicits robust CD8 ⁺ T cell response

Jinjin Chen, Zhongfeng Ye, Changfeng Huang et al. · Proceedings of the National Academy of Sciences · 2022 · 400 citations · Full text

Pharmacy, Immunology, Pharmaceutics +17

In Vitro Engineering Chimeric Antigen Receptor Macrophages and T Cells by Lipid Nanoparticle-Mediated mRNA Delivery

Zhongfeng Ye, Jinjin Chen, Xuewei Zhao et al. · ACS Biomaterials Science & Engineering · 2022 · 102 citations

Life Sciences, Biotechnology, Immunology +17

Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants

Zhongfeng Ye, Srinivasa Reddy Bonam, Lindsay G. A. McKay et al. · Proceedings of the National Academy of Sciences · 2023 · 24 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

In vivo base editing of Angptl3 via lipid nanoparticles to treat cardiovascular disease

Jennifer Khirallah, Hanan Bloomer, Douglas Wich et al. · Molecular Therapy — Nucleic Acids · 2025 · 17 citations · Full text

Pharmacy, Molecular Medicine, Pharmacology +17