Suzanne Beckham

A photochemically triggered DNA cleaving agent: synthesis, mechanistic and DNA cleavage studies on a new analog of the anti-tumor antibiotic dynemicin

Paul A. Wender, Charles K. Zercher, Suzanne Beckham et al. · The Journal of Organic Chemistry · 1993 · 74 citations

Medicine, Medicinal Chemistry, Oncology +12

Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes.

Paul A. Wender, Robert C. Kelly, Suzanne Beckham et al. · Proceedings of the National Academy of Sciences · 1991 · 39 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

The intramolecular addition of silylated alkynes to aldehydes: Methodology for the construction of cyclic enediynes and its application to dynemicin analogs

Paul A. Wender, Suzanne Beckham, Debra L. Mohler · Tetrahedron Letters · 1995 · 38 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13

A Second Generation Photochemically Activatable Dynemicin Analog: A Concise Synthesis and DNA Cleavage Studies

Paul A. Wender, Suzanne Beckham, Jacqueline G. O’Leary · Synthesis · 1994 · 31 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6