The Antifungal Activity of RsAFP2, a Plant Defensin from <i>Raphanus sativus</i>, Involves the Induction of Reactive Oxygen Species in <i>Candida albicans</i>

An Aerts, Isabelle François, Els Meert, +3

Microbial Physiology

DmAMP1, an antifungal plant defensin from dahlia (<i>Dahlia merckii</i>), interacts with sphingolipids from<i>Saccharomyces cerevisiae</i>

Karin Thevissen, Isabelle E.J.A François, Jon Y. Takemoto, +3

FEMS Microbiology Letters

BiologyBiosynthesisBiochemistryFungal PathogenResistance Towards Dmamp1 +12

Repurposing as a means to increase the activity of amphotericin B and caspofungin against Candida albicans biofilms

Nicolas Delattin, Klaas De Brucker, Katleen Vandamme, +5

Journal of Antimicrobial Chemotherapy

Miconazole Induces Changes in Actin Cytoskeleton prior to Reactive Oxygen Species Induction in Yeast

Karin Thevissen, Kathryn R. Ayscough, An Aerts, +6

Journal of Biological Chemistry

<i>SKN1</i>, a novel plant defensin‐sensitivity gene in <i>Saccharomyces cerevisiae</i>, is implicated in sphingolipid biosynthesis

Karin Thevissen, Jola Idkowiak-Baldys, Y.J. Im, +8

FEBS Letters

Fungicidal activity of truncated analogues of dihydrosphingosine

Karin Thevissen, Ulrik Hillaert, Els Meert, +4

Bioorganic & Medicinal Chemistry Letters

BiosynthesisMedicinal FungiBiochemistryTruncated Analogues

Potentiation of Antibiofilm Activity of Amphotericin B by Superoxide Dismutase Inhibition

Katrijn De Brucker, Anna Bink, Els Meert, +2

Oxidative Medicine and Cellular Longevity

Superoxide Dismutase InhibitionBiofilm CellsAntimicrobial ChemotherapyDrug ResistanceAmphotericin B +14

Design and Synthesis of a Series of Piperazine‐1‐carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species

Isabelle François, Karin Thevissen, Klaartje Pellens, +13

ChemMedChem

Bioorganic ChemistryPharmaceutical ChemistryRedox BiologyMedicinal ChemistryBiosynthesis +14

Novel fungicidal benzylsulfanyl-phenylguanidines

Karin Thevissen, Klaartje Pellens, Katrijn De Brucker, +11

Bioorganic & Medicinal Chemistry Letters

Derivative (Chemistry)Bioorganic ChemistryOrganic ChemistryPharmacologyPharmaceutical Chemistry

The nutrient-responsive CDK Pho85 primes the Sch9 kinase for its activation by TORC1

Marie-Anne Deprez, Marco Caligaris, Joëlle Rosseels, +11

PLoS Genetics