TorsinA participates in endoplasmic reticulum-associated degradation

Flávia C. Nery, Ioanna A. Armata, Jonathan E. Farley, +13

Nature Communications

Signal TransductionEndocytic PathwayCytoskeletonTorsina ParticipatesIntracellular Trafficking +5

Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells

Kelsey Pinkham, Jae‐Hyun Park, Arsalan Hashemiaghdam, +11

Stem Cell Reports

AAV9 transduction mediated by systemic delivery of vector via retro-orbital injection in newborn, neonatal and juvenile mice

Shilpa Prabhakar, Sevda Lüle, Cintia Carla da Hora, +2

EXPERIMENTAL ANIMALS

In Vivo Gene TherapySynthetic VirologyImmunologyGene DeliveryBiomedical Engineering +15

Dissecting inherent intratumor heterogeneity in patient-derived glioblastoma culture models

Jian Teng, Cintia Carla da Hora, Rami S. Kantar, +6

Neuro-Oncology

Biochemical and Cellular Analysis of Human Variants of the DYT1 Dystonia Protein, TorsinA/TOR1A

Jasmin Hettich, Scott D. Ryan, Osmar Norberto de Souza, +11

Human Mutation

Cellular AnalysisGeneticsPathologyMolecular GeneticsDisease Gene Identification +16

Sustained NF-κB-STAT3 signaling promotes resistance to Smac mimetics in Glioma stem-like cells but creates a vulnerability to EZH2 inhibition

Cintia Carla da Hora, Kelsey Pinkham, Litia Carvalho, +5

Cell Death Discovery

Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation

Christian E. Badr, Cintia Carla da Hora, Aleksandar B. Kirov, +12

ACS Chemical Biology

Chemoprevention StrategyCysteine-modifying CompoundGliomaTumor BiologyOxidative Stress +14

A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo

Jasper Che-Yung Chien, Elie Tabet, Kelsey Pinkham, +5

Nucleic Acids Research

EngineeringMultiplexed Bioluminescent ReporterDna AnalysisMolecular BiologyDsb Repair +16

New methods for investigation of neuronal migration in embryonic brain explants

Flávia C. Nery, Cintia Carla da Hora, Uzma Yaqub, +5

Journal of Neuroscience Methods

NeuroregenerationDevelopmental BiologyCellular NeurobiologyNeurophysiologyNeuroanatomy +12

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia

Flávia C. Nery, Cintia Carla da Hora, Nadia A. Atai, +5

Journal of Neuroscience Methods

EngineeringOrgan-on-a-chipDyt1 DystoniaMicrofluidic PlatformBiomedical Engineering +2