Concepedia

Isaac Sappington

IS

Statistics

Publications

8

Citations

2K

H-Index

8

Active since

2022

Affiliations

University of Washington(Current)

Howard Hughes Medical Institute

Massachusetts Institute of Technology

Harvard University

University of Cambridge

Isaac Sappington is an author at University of Washington specializing in structural biology, deep learning, and bioinformatics.

ORCID

Top concepts

Publications per year

2022–2025

8

Publications

8

De novo design of protein structure and function with RFdiffusion

Joseph L. Watson, David Juergens, Nathaniel R. Bennett et al. · Nature · 2023 · 1.6K citations · Full text

Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models

Joseph L. Watson, David Juergens, Nathaniel R. Bennett et al. · 2022 · 144 citations · Full text

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Designed endocytosis-inducing proteins degrade targets and amplify signals

Buwei Huang, Mohamad H. Abedi, Green Ahn et al. · Nature · 2024 · 97 citations · Full text

De novo designed proteins neutralize lethal snake venom toxins

Susana Vázquez Torres, Melisa Bénard-Valle, Stephen P. Mackessy et al. · Nature · 2025 · 88 citations · Full text

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

Benjamin J. Read, Lori Won, John C. Kraft et al. · Cell Reports · 2022 · 55 citations · Full text

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