Jamal B. Williams

Targeting histone K4 trimethylation for treatment of cognitive and synaptic deficits in mouse models of Alzheimer’s disease

Qing Cao, Wei Wang, Jamal B. Williams et al. · Science Advances · 2020 · 107 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Transcriptomic analysis of human brains with Alzheimer’s disease reveals the altered expression of synaptic genes linked to cognitive deficits

Jamal B. Williams, Qing Cao, Zhen Yan · Brain Communications · 2021 · 74 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15

Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4

Benjamin Rein, Tao Tan, Fengwei Yang et al. · Molecular Psychiatry · 2020 · 63 citations · Full text

Life Sciences, Molecular Genetics, Neuroscience +16

Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures

Luye Qin, Jamal B. Williams, Tao Tan et al. · Nature Communications · 2021 · 60 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Autism risk gene KMT5B deficiency in prefrontal cortex induces synaptic dysfunction and social deficits via alterations of DNA repair and gene transcription

Zijun Wang, Ping Zhong, Jamal B. Williams et al. · Neuropsychopharmacology · 2021 · 49 citations · Full text

Life Sciences, Genetics, Neuroscience +15