Gaoxin Lei

Lunasin attenuates oxidant‐induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE ^−/− mice by up‐regulating heme oxygenase‐1 <i>via</i> PI3K/Akt/Nrf2/ARE pathway

Lili Gu, Pei Ye, Hengli Li et al. · The FASEB Journal · 2019 · 55 citations

Life Sciences, Biochemistry, Pharmacology +17

Lunasin functionally enhances LDL uptake via inhibiting PCSK9 and enhancing LDLR expression <i>in vitro</i> and <i>in vivo</i>

Lili Gu, Yue Wang, Ya‐Qiong Xu et al. · Oncotarget · 2017 · 28 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy

Menglong Xu, Gaoxin Lei, Manman Chen et al. · EBioMedicine · 2021 · 18 citations · Full text

Pharmacy, Biotechnology, Pharmacology +17

Lunasin Improves the LDL-C Lowering Efficacy of Simvastatin via Inhibiting PCSK9 Expression in Hepatocytes and ApoE−/− Mice

Lili Gu, Yaqin Gong, Cheng Zhao et al. · Molecules · 2019 · 12 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo

Gaoxin Lei, Menglong Xu, Zhipan Xu et al. · International Journal of Molecular Sciences · 2017 · 10 citations · Full text

Life Sciences, Oncology, Pharmacology +17