Sina Saffaran

High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study

Liam Weaver, Anup Das, Sina Saffaran et al. · Annals of Intensive Care · 2021 · 82 citations · Full text

Medicine, Physiology, Physiological Systems Modeling +15

CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-β Signaling in Prostate Cancer

Hoda Kardooni, Estela González‐Gualda, Emmanouil Stylianakis et al. · Cancers · 2018 · 56 citations · Full text

Life Sciences, Cancer Biology, Oncology +15

Utility of Driving Pressure and Mechanical Power to Guide Protective Ventilator Settings in Two Cohorts of Adult and Pediatric Patients With Acute Respiratory Distress Syndrome: A Computational Investigation

Sina Saffaran, Anup Das, John G. Laffey et al. · Critical Care Medicine · 2020 · 40 citations · Full text

Medicine, Pediatrics, Respiratory Therapy +17

In Silico Modeling of Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Pathophysiologic Insights and Potential Management Implications

Anup Das, Sina Saffaran, Marc Chikhani et al. · Critical Care Explorations · 2020 · 22 citations · Full text

Medicine, Infectious Diseases, Physiological Systems Modeling +16

Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation

Liam Weaver, Hossein Shamohammadi, Sina Saffaran et al. · Critical Care Medicine · 2024 · 16 citations · Full text

Medicine, Clinical Sciences, Respiratory Therapy +17