Misako Wakita

The rationale for E2020 as a potent acetylcholinesterase inhibitor

Yoshiyuki Kawakami, Atsushi Inoue, Takatoshi Kawai et al. · Bioorganic & Medicinal Chemistry · 1996 · 123 citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

The Simulated Binding of (±)-2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1<i>H</i>-inden-1-one Hydrochloride (E2020) and Related Inhibitors to Free and Acylated Acetylcholinesterases and Corresponding Structure−Activity Analyses

Atsushi Inoue, Takatoshi Kawai, Misako Wakita et al. · Journal of Medicinal Chemistry · 1996 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Locations of local anesthetic dibucaine in model membranes and the interaction between dibucaine and a Na+ channel inactivation gate peptide as studied by 2H- and 1H-NMR spectroscopies

Yoshihiro Kuroda, Minetaro Ogawa, H. Nasu et al. · Biophysical Journal · 1996 · 45 citations · Full text

Natural Sciences, Biophysics, Pharmacology +17

Conformations of dibucaine and tetracaine in small unilamellar phosphatidylcholine vesicles as studied by nuclear Overhauser effects in 1H nuclear magnetic resonance spectroscopy

Misako Wakita, Yoshihiro Kuroda, Yasuhiro Fujiwara et al. · Chemistry and Physics of Lipids · 1992 · 23 citations

Life Sciences, Biochemistry, Chemistry +16