BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway

Adam L. Green, John DeSisto, Patrick Flannery, +28

Oncogene

Pediatric Brain TumorsGliomaMedicinePathologyCancer Cell Biology +9

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

John DeSisto, John T. Lucas, Ke Xu, +30

Nature Communications

Acute Psychosis Due to Anti-N-Methyl D-Aspartate Receptor Encephalitis Following COVID-19 Vaccination: A Case Report

Patrick Flannery, Ingrid Yang, Madjid Keyvani, +1

Frontiers in Neurology

NeuropsychiatryCovid-19Anti-nmdar EncephalitisNeurologyCovid-19 Vaccination +15

Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR

Satyanarayana R. Pondugula, Patrick Flannery, Kodye L. Abbott, +4

Toxicology Letters

Molecular PharmacologyMolecular PathwayHuman PxrMedicineNatural Sciences +7

Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma

Patrick Flannery, John DeSisto, Vladimir Amani, +10

Oncology Reports

High-grade GliomasPreclinical AnalysisGliomaTumor BiologyMtorc1 Inhibitor Everolimus +14

Pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinolines: Novel compounds that reverse ABCG2-mediated resistance in cancer cells

Chandrabose Karthikeyan, Ritu Malla, Charles R. Ashby, +11

Cancer Letters

Drug Resistance AnalysisBiochemistryMedicineAnti-cancer AgentCancer Cells +3

Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine

Adam L. Green, Patrick Flannery, Todd C. Hankinson, +20

Neuro-Oncology Advances

Exportin 1 Inhibition Induces Nerve Growth Factor Receptor Expression to Inhibit the NF-κB Pathway in Preclinical Models of Pediatric High-Grade Glioma

John DeSisto, Patrick Flannery, Rakeb Lemma, +12

Molecular Cancer Therapeutics

Mg2+/Mn2+-Dependent Phosphatase 1A Is Involved in Regulating Pregnane X Receptor–Mediated Cytochrome p450 3A4 Gene Expression

Satyanarayana R. Pondugula, Patrick Flannery, Udayan Apte, +5

Drug Metabolism and Disposition

Correlation of PPM1A Downregulation with CYP3A4 Repression in the Tumor Liver Tissue of Hepatocellular Carcinoma Patients

Patrick Flannery, Kodye L. Abbott, Satyanarayana R. Pondugula

European Journal of Drug Metabolism and Pharmacokinetics

Tumor BiologyHepatologyHepatocellular CarcinomaLiver PhysiologyPathology +10