David A. Hottman

Farnesyltransferase Haplodeficiency Reduces Neuropathology and Rescues Cognitive Function in a Mouse Model of Alzheimer Disease

Shaowu Cheng, Dongfeng Cao, David A. Hottman et al. · Journal of Biological Chemistry · 2013 · 42 citations · Full text

Synaptic Transmission, Molecular Biology, Neurochemical Biomarkers +26

Simvastatin Treatment Enhances NMDAR-Mediated Synaptic Transmission by Upregulating the Surface Distribution of the GluN2B Subunit

Marc-Alexander L. T. Parent, David A. Hottman, Shaowu Cheng et al. · Cellular and Molecular Neurobiology · 2014 · 39 citations · Full text

Synaptic Plasticity, Molecular Physiology, Neurophysiology +13

Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density

David A. Hottman, Shaowu Cheng, Andrea Gram et al. · Neuroscience · 2018 · 23 citations · Full text

Synaptic Plasticity, Molecular Neuroscience, Dendritic Spines +12

Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function

Wenhui Qu, Kiall F. Suazo, Wenfeng Liu et al. · Molecular Neurobiology · 2020 · 21 citations · Full text

Synaptic Plasticity, Medicine, Cortical Remodeling +9

Haplodeficiency of <i>Cathepsin D</i> does not affect cerebral amyloidosis and autophagy in <scp>APP</scp>/<scp>PS</scp>1 transgenic mice

Shaowu Cheng, Willayat Yousuf Wani, David A. Hottman et al. · Journal of Neurochemistry · 2017 · 18 citations · Full text

Lysosomal Function, Transgenic Mice, Synaptic Signaling +19