Takashi Seishi

Potent and Selective Inhibitors of Platelet-Derived Growth Factor Receptor Phosphorylation. 3. Replacement of Quinazoline Moiety and Improvement of Metabolic Polymorphism of 4-[4-(<i>N</i>-Substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline Derivatives

Kenji Matsuno, Junko Ushiki, Takashi Seishi et al. · Journal of Medicinal Chemistry · 2003 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmacological Study +15

Stemodin synthesis (II) — highly diastereoselective formal total synthesis of − -stemodin via Pd2+-promoted cycloalkenylation reaction

Masahiro Toyota, Takashi Seishi, Keiichiro Fukumoto · Tetrahedron · 1994 · 17 citations

Diversity Oriented Synthesis, Engineering, Biochemistry +9

Pd2+-promoted cyclization in tetracyclic diterpene synthesis highly diastereoselective formal total synthesis of (±)-stemodin

Masahiro Toyota, Takashi Seishi, Keiichiro Fukumoto · Tetrahedron Letters · 1993 · 13 citations

Pd2+-promoted Cyclization, Diversity Oriented Synthesis, Engineering +8

Aphidicolin synthesis (I)—formal synthesis of (±)-aphidicolin by the successive intramolecular Diels-Alder reactions

Masahiro Toyota, Youichi Nishikawa, Takashi Seishi et al. · Tetrahedron · 1994 · 13 citations

Biosynthesis, Engineering, Aphidicolin Synthesis +7

Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. Part 4: structure–activity relationships for substituents on the quinazoline moiety of 4-[4-(N-substituted(thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives

Kenji Matsuno, Takashi Seishi, Takao Nakajima et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 11 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +12