Siddharth Kaul

Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase Cδ Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl

Vellareddy Anantharam, Masashi Kitazawa, Jarrad R. Wagner et al. · Journal of Neuroscience · 2002 · 219 citations · Full text

Mitophagy, Manganese Compound, Apoptosis +21

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP⁺)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

Siddharth Kaul, Arthi Kanthasamy, Masashi Kitazawa et al. · European Journal of Neuroscience · 2003 · 165 citations

Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells

Vellareddy Anantharam, Siddharth Kaul, Chunjuan Song et al. · NeuroToxicology · 2007 · 115 citations · Full text

Biochemistry, Medicine, Lipid Peroxidation +9

Tyrosine Phosphorylation Regulates the Proteolytic Activation of Protein Kinase Cδ in Dopaminergic Neuronal Cells

Siddharth Kaul, Vellareddy Anantharam, Yongjie Yang et al. · Journal of Biological Chemistry · 2005 · 114 citations · Full text

Suppression of caspase-3-dependent proteolytic activation of protein kinase Cδ by small interfering RNA prevents MPP+-induced dopaminergic degeneration

Yongjie Yang, Siddharth Kaul, Danhui Zhang et al. · Molecular and Cellular Neuroscience · 2004 · 72 citations

Signal Transduction, Caspase-3-dependent Proteolytic Activation, Signaling Pathway +8