The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signalling

Kohei Uchimura, Manabu Hayata, Teruhiko Mizumoto, +16

Nature Communications

In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats

Kohei Uchimura, Yutaka Kakizoe, Tomoaki Onoue, +11

American Journal of Physiology-Renal Physiology

Renal InflammationSerine ProteasesExperimental PharmacologyCellular PhysiologyBlood Pressure +21

Effect of a serine protease inhibitor on the progression of chronic renal failure

Manabu Hayata, Yutaka Kakizoe, Kohei Uchimura, +11

American Journal of Physiology-Renal Physiology

HypertensionRenal InflammationSerine ProteasesOxidative StressGlomerulonephritis +16

Suppressed ER‐associated degradation by intraglomerular cross talk between mesangial cells and podocytes causes podocyte injury in diabetic kidney disease

Daisuke Fujimoto, Takashige Kuwabara, Yusuke Hata, +9

The FASEB Journal

ApoptosisImmunologyRenal InflammationCell DeathCross Talk +17

The antifibrotic effect of a serine protease inhibitor in the kidney

Jun Morinaga, Yutaka Kakizoe, Taku Miyoshi, +11

American Journal of Physiology-Renal Physiology

Renal PathologyRenal InflammationPathologySerine Protease InhibitorsGlomerulonephritis +20

The Serine Protease Inhibitor Camostat Mesilate Attenuates the Progression of Chronic Kidney Disease through its Antioxidant Effects

Miki Ueda, Kohei Uchimura, Yuki Narita, +12

˜The œNephron journals/Nephron journals

Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model

Yuki Narita, Miki Ueda, Kohei Uchimura, +13

Journal of Pharmacological Sciences

HypertensionRenal FunctionRenal DiseaseRat Ckd ModelsMedicine +13

Pembrolizumab-associated thrombotic microangiopathy in a patient with urothelial cancer: a case report and literature review

Manabu Hayata, Masaya Shimanuki, Takehiro Ko, +6

Renal Replacement Therapy

Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study

Jun Morinaga, Tatsuyuki Kakuma, Hirotaka Fukami, +21

Nephrology Dialysis Transplantation

A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity

Yutaka Kakizoe, Yoshikazu Miyasato, Tomoaki Onoue, +11

Journal of Pharmacological Sciences