Manal Abdel Fattah Ezzat

Design, synthesis, in vitro and in vivo evaluation of novel pyrrolizine-based compounds with potential activity as cholinesterase inhibitors and anti-Alzheimer's agents

Nehad A. El‐Sayed, Awatef El-Said Farag, Manal Abdel Fattah Ezzat et al. · Bioorganic Chemistry · 2019 · 59 citations

Potential Activity, Medicinal Chemistry, Biochemistry +8

Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer’s disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation

Esraa Abdo Moustafa, Heba Abdelrasheed Allam, Marwa A. Fouad et al. · Bioorganic Chemistry · 2024 · 16 citations

Alzheimer's Disease, Biochemistry, Potential Gsk-3β Inhibitors +8

Design, synthesis, and biological evaluation of furan‐bearing pyrazolo[3,4‐<i>b</i>]pyridines as novel inhibitors of CDK2 and P53–MDM2 protein–protein interaction

Manal Abdel Fattah Ezzat, Ghada F. Elmasry, Menna M. A. Abd El‐Mageed et al. · Drug Development Research · 2023 · 13 citations

Design, synthesis, in vitro, and in vivo evaluation of novel phthalazinone‐based derivatives as promising acetylcholinesterase inhibitors for treatment of Alzheimer's disease

Manal Abdel Fattah Ezzat, Sara Mohamed Abdelhamid, Marwa A. Fouad et al. · Drug Development Research · 2023 · 10 citations