Coby Out

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS

Wieke Zuidervaart, Frans van Nieuwpoort, Mitchell Stark et al. · British Journal of Cancer · 2005 · 217 citations · Full text

Medicine, Molecular Biology, Oncology +17

Increased Melanogenesis is a Risk Factor for Oxidative DNA Damage— Study on Cultured Melanocytes and Atypical Nevus Cells^†

Nico P.M. Smit, Frans A. van Nieuwpoort, Laurent Marrot et al. · Photochemistry and Photobiology · 2007 · 93 citations

Life Sciences, Cell Biology, Molecular Biology +17

Disturbed melanin synthesis and chronic oxidative stress in dysplastic naevi

Stan Pavel, Frans van Nieuwpoort, H. van der Meulen et al. · European Journal of Cancer · 2004 · 84 citations

Life Sciences, Dermatology, Pathobiology +16

Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II molecules

A. Mieke Mommaas, Aat A. Mulder, Reina Jordens et al. · European Journal of Immunology · 1999 · 57 citations

Life Sciences, Cell Biology, Immunology +17

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Jun Fang, Jinping Jia, Matthew Makowski et al. · Nature Communications · 2017 · 54 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13