David J. Hughes

Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

Marie‐Christine Chartier‐Harlin, Fiona Crawford, Henry Houlden et al. · Nature · 1991 · 1.2K citations

Neurodegenerative Diseases, Codon 717, Alzheimer's Disease +10

A common coding variant in CASP8 is associated with breast cancer risk

Angela Cox, Alison M. Dunning, Montserrat García‐Closas et al. · Nature Genetics · 2007 · 610 citations

Breast Oncology, Oncology, Cancer Epidemiology +12

Fusobacterium nucleatum associates with stages of colorectal neoplasia development, colorectal cancer and disease outcome

L. Flanagan, Jasmin Schmid, Martin A. Ebert et al. · European Journal of Clinical Microbiology & Infectious Diseases · 2014 · 507 citations

Medicine, Colorectal Cancer, Pathology +4

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis

Alasdair Scott, James L. Alexander, Claire A Merrifield et al. · Gut · 2019 · 262 citations · Full text

RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

Antonis C. Antoniou, Olga M. Sinilnikova, Jacques Simard et al. · The American Journal of Human Genetics · 2007 · 242 citations · Full text

Genome Instability, Breast Oncology, Brca2 Mutation Carriers +11