Yusuke Higashi

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

Yasuyuki Fujimoto, Hiroyuki Itabe, Jun Sakai et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2003 · 329 citations

Life Sciences, Biochemistry, Cell Biology +12

IGF-1 Reduces Inflammatory Responses, Suppresses Oxidative Stress, and Decreases Atherosclerosis Progression in ApoE-Deficient Mice

Sergiy Sukhanov, Yusuke Higashi, Shaw‐Yung Shai et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2007 · 276 citations

Veterinary Medicine, Cardiology, Pathobiology +17

Involvement of ACSL in local synthesis of neutral lipids in cytoplasmic lipid droplets in human hepatocyte HuH7

Yasuyuki Fujimoto, Hiroyuki Itabe, Tetsuaki Kinoshita et al. · Journal of Lipid Research · 2007 · 170 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient Mice

Yusuke Higashi, Sergiy Sukhanov, Shaw‐Yung Shai et al. · Circulation · 2016 · 117 citations · Full text

Life Sciences, Cell Biology, Pathobiology +17

The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretion

Sergiy Sukhanov, Yusuke Higashi, Tadashi Yoshida et al. · Cellular Signalling · 2020 · 111 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16