Paul Renton

Discovery of<i>cis</i>-<i>N</i>-(1-(4-(Methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: A 1,6-Disubstituted Indoline Derivative as a Highly Selective Inhibitor of Human Neuronal Nitric Oxide Synthase (nNOS) without Any Cardiovascular Liabilities

Subhash C. Annedi, Jailall Ramnauth, Shawn P. Maddaford et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Novel 2-aminobenzothiazoles as selective neuronal nitric oxide synthase inhibitors

Joanne Patman, Namrta Bhardwaj, Jailall Ramnauth et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 32 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Design, Synthesis, and Biological Evaluation of 3,4-Dihydroquinolin-2(1<i>H</i>)-one and 1,2,3,4-Tetrahydroquinoline-Based Selective Human Neuronal Nitric Oxide Synthase (nNOS) Inhibitors

Jailall Ramnauth, Joanne Speed, Shawn P. Maddaford et al. · Journal of Medicinal Chemistry · 2011 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Applications of Organocatalytic Asymmetric Synthesis to Drug Prototypes—Dual Action and Selective Inhibitors of <i>n</i>-Nitric Oxide Synthase with Activity Against the 5-HT_1D/1B Subreceptors

Stephen Hanessian, Eli Stoffman, Xueling Mi et al. · Organic Letters · 2011 · 26 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

NOpiates: Novel Dual Action Neuronal Nitric Oxide Synthase Inhibitors with μ-Opioid Agonist Activity

Paul Renton, Brenda J. Green, Shawn P. Maddaford et al. · ACS Medicinal Chemistry Letters · 2012 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17