Peter H. Dobbelaar

Regulation of Energy Homeostasis by Bombesin Receptor Subtype-3: Selective Receptor Agonists for the Treatment of Obesity

Xiao-Ming Guan, Howard Chen, Peter H. Dobbelaar et al. · Cell Metabolism · 2010 · 87 citations · Full text

Obesity, Metabolic Syndrome, Energy Homeostasis +11

Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity

Jian Liu, Shuwen He, Tianying Jian et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 29 citations · Full text

Medicinal Chemistry, Drug Target, Bombesin Receptor +8

Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists

Shuwen He, Peter H. Dobbelaar, Jian Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 24 citations · Full text

Substituted Biphenyl Imidazoles, Medicinal Chemistry, Drug Target +8

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Shrenik K. Shah, Shuwen He, Liangqin Guo et al. · ACS Medicinal Chemistry Letters · 2015 · 23 citations · Full text

Development Candidate, Cardiovascular Pharmacology, Pharmacotherapy +17

Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist

Shuwen He, Zhixiong Ye, Peter H. Dobbelaar et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 23 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +7