Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28

Daniela Di Bella, Federico Lazzaro, Alfredo Brusco, +23

Nature Genetics

Mitochondrial FunctionGenetic DisorderGeneticsMolecular BiologyMolecular Genetics +2

The DNA Damage Checkpoint Response Requires Histone H2B Ubiquitination by Rad6-Bre1 and H3 Methylation by Dot1

Michele Giannattasio, Federico Lazzaro, Paolo Plevani, +1

Journal of Biological Chemistry

Histone ModificationsChromatinGenome InstabilityChromatin RemodelingMedicine +12

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

Federico Lazzaro, Vasileia Sapountzi, Magda Granata, +6

The EMBO Journal

Histone ModificationsChromatinGenome InstabilityChromatin RemodelingHistone Methyltransferase Dot1 +9

RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA

Federico Lazzaro, Daniele Novarina, Flavio Amara, +7

Molecular Cell

ChromatinGenome InstabilityRnase HNatural SciencesGenetics +8

Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

Medini M. Ghodgaonkar, Federico Lazzaro, Maite Olivera-Pimentel, +7

Molecular Cell

ChromatinGenome InstabilityRibonucleotides MisincorporatedStrand-discrimination SignalsNatural Sciences +7

Functional Interplay between the 53BP1-Ortholog Rad9 and the Mre11 Complex Regulates Resection, End-Tethering and Repair of a Double-Strand Break

Matteo Ferrari, Diego Dibitetto, Giuseppe De Gregorio, +7

PLoS Genetics

ChromatinGenome InstabilityDna FilamentsDouble-strand BreakChromatin Remodeling +12

Phosphorylation of the Budding Yeast 9-1-1 Complex Is Required for Dpb11 Function in the Full Activation of the UV-Induced DNA Damage Checkpoint

Fabio Puddu, Magda Granata, Lisa di Nola, +6

Molecular and Cellular Biology

Exo1 Competes with Repair Synthesis, Converts NER Intermediates to Long ssDNA Gaps, and Promotes Checkpoint Activation

Michele Giannattasio, Cindy Follonier, Hélène Tourrière, +6

Molecular Cell

Genome InstabilityNatural SciencesGenomic MechanismDna ReplicationMolecular Biology +6

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint

Michele Giannattasio, Federico Lazzaro, Maria Pia Longhese, +2

The EMBO Journal

ChromatinGenome InstabilityDna DamageFunctional InteractionsMedicine +6

Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice

Vittoria Brambilla, Damiano Martignago, Daniela Goretti, +8

The Plant Cell