Karin Knobe

Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial

Peter W. Collins, Guy Young, Karin Knobe et al. · Blood · 2014 · 180 citations · Full text

Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B

Claude Négrier, Karin Knobe, Andreas Tiede et al. · Blood · 2011 · 179 citations · Full text

Enhancing the pharmacokinetic properties of recombinant factor VIII: first-in-human trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A

Andreas Tiede, B. Brand, R. Fischer et al. · Journal of Thrombosis and Haemostasis · 2013 · 164 citations

Pharmacology, Hematology, Recombinant Factor Viii +6

Efanesoctocog Alfa Prophylaxis for Patients with Severe Hemophilia A

Annette von Drygalski, Pratima Chowdary, Roshni Kulkarni et al. · New England Journal of Medicine · 2023 · 160 citations · Full text

Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide

Jais Rose Bjelke, Lene Hansen, Lars C. Petersen et al. · Blood · 2011 · 136 citations · Full text