Helma van den Hurk

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients

Fred W. van Leeuwen, Dominique P.V. de Kleijn, Helma van den Hurk et al. · Science · 1998 · 568 citations

Life Sciences, Molecular Biology, Neuroscience +17

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

Elliot D. Mock, Mohammed Ahmed Mustafa, Ozge Gunduz‐Cinar et al. · Nature Chemical Biology · 2020 · 96 citations · Full text

Medicine, Neuroscience, Pharmacology +8

Enzymic characterization of immunopurified prohormone convertase 2: Potent inhibition by a 7B2 peptide fragment

Iris Lindberg, Helma van den Hurk, Chau Bui et al. · Biochemistry · 1995 · 76 citations

Life Sciences, Biochemistry, Pharmacology +8

Identification of the Region within the Neuroendocrine Polypeptide 7B2 Responsible for the Inhibition of Prohormone Convertase PC2

A. Martin Van Horssen, Helma van den Hurk, E M Bailyes et al. · Journal of Biological Chemistry · 1995 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Ming Jiang, Mirjam Huizenga, Jonah L. Wirt et al. · Nature Communications · 2023 · 52 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16