Roman P. Jakob

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase

Hundeep Kaur, Roman P. Jakob, Jan K. Marzinek et al. · Nature · 2021 · 231 citations

Antimicrobial Drug Discovery, Antimicrobial Susceptibility, Antibiotics +10

Catch-bond mechanism of the bacterial adhesin FimH

Maximilian M. Sauer, Roman P. Jakob, Jonathan Eras et al. · Nature Communications · 2016 · 224 citations · Full text

The structural basis of autotransporter translocation by TamA

Fabian Gruss, Franziska Zähringer, Roman P. Jakob et al. · Nature Structural & Molecular Biology · 2013 · 134 citations

Natural Sciences, Membrane Transport, Molecular Biology +3

Computational identification of a systemic antibiotic for Gram-negative bacteria

Ryan D. Miller, Akira Iinishi, Seyed Majed Modaresi et al. · Nature Microbiology · 2022 · 128 citations · Full text

Antimicrobial Resistance Gene, Antimicrobial Susceptibility, Antibiotics +6

Long-lived T follicular helper cells retain plasticity and help sustain humoral immunity

Marco Künzli, David Schreiner, Tamara C. Pereboom et al. · Science Immunology · 2020 · 114 citations