Sofie V. Nielsen

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

P.R. Elliott, Sofie V. Nielsen, Paola Marco‐Casanova et al. · Molecular Cell · 2014 · 187 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

Anna Mosbech, Ian Gibbs‐Seymour, Konstantinos Kagias et al. · Nature Structural & Molecular Biology · 2012 · 175 citations

Life Sciences, Genetics, Molecular Biology +16

Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance

Matteo Cagiada, Kristoffer E. Johansson, Audronė Valančiūtė et al. · Molecular Biology and Evolution · 2021 · 133 citations · Full text

Life Sciences, Biology, Evolutionary Biology +17

Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

Sofie V. Nielsen, Amelie Stein, Alexander B. Dinitzen et al. · PLoS Genetics · 2017 · 120 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

Amanda B. Abildgaard, Amelie Stein, Sofie V. Nielsen et al. · eLife · 2019 · 76 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17