Two Structures of Cyclophilin 40

Paul Taylor, Jacqueline Dornan, Amerigo Carrello, +3

Structure

Cyclophilin 40Bioorganic ChemistryProtein AssemblyBiochemistryProtein Folding +7

First Crystal Structure of a Medicinally Relevant Gold Protein Complex: Unexpected Binding of [Au(PEt3)]+ to Histidine

Juan Zou, Paul Taylor, Jacqueline Dornan, +3

Angewandte Chemie International Edition

Protein AssemblyCys Thiol GroupsMolecular BiologyProtein X-ray CrystallographyStructure Elucidation +17

Immunodetection of PrPSc in spleens of some scrapie-infected sheep but not BSE-infected cows.

R. A. Somerville, Christopher R. Birkett, James D. Foster, +8

Journal of General Virology

ImmunologyPathologyEducationLivestock HealthPrpsc Deposition +15

Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie

Christine Farquhar, Jacqueline Dornan, R. A. Somerville, +2

Journal of General Virology

Mice CongenicSinc GenotypeNeurovirologyMedicinePathogenesis +11

A Structure-based Mutational Analysis of Cyclophilin 40 Identifies Key Residues in the Core Tetratricopeptide Repeat Domain That Mediate Binding to Hsp90

Bryan K. Ward, Rudi K. Allan, D. Mok, +8

Journal of Biological Chemistry

Hsp90 BindingBiomolecular Structure PredictionStructural BioinformaticsImmunologyMolecular Biology +19

Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis elegans

Jacqueline Dornan, Antony P. Page, Paul Taylor, +4

Journal of Biological Chemistry

Neutralizing and enhancing activities of human respiratory syncytial virus-specific antibodies

H. B. Gimenez, Sirilada Pimpa Chisholm, Jacqueline Dornan, +1

Clinical and Diagnostic Laboratory Immunology

VaccinationRsv PathologyRespiratory Virus ImmunityMolecular VirologyRespiratory Diseases +11

Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice

I.W. McNae, James Kinkead, Divya Malik, +18

Nature Communications

Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy

Christine Farquhar, Jacqueline Dornan, Richard C. Moore, +3

Journal of General Virology

Structural role of the flanking DNA in mariner transposon excision

Jacqueline Dornan, Heather Grey, J. Richardson

Nucleic Acids Research

Crystal StructureGeneticsDna AnalysisMolecular BiologyMolecular Genetics +15