William Senapedis

CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications

Y-T Tai, Yosef Landesman, Chirag Acharya et al. · Leukemia · 2013 · 299 citations · Full text

Tumor Biology, Oncology, Bone Morphogenic Protein +10

Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma

Yan-Yi Jiang, De‐Chen Lin, Anand Mayakonda et al. · Gut · 2016 · 233 citations · Full text

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer

Jimi Kim, Elizabeth A. McMillan, Hyun Seok Kim et al. · Nature · 2016 · 207 citations · Full text

Tumor Biology, Xpo1-dependent Nuclear Export, Oncology +10

PAK4 inhibition improves PD-1 blockade immunotherapy

Gabriel Abril-Rodríguez, Davis Y. Torrejon, Wei Liu et al. · Nature Cancer · 2019 · 154 citations · Full text

Pak4 Inhibition, Immunology, Tumor Immunity +5

Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth

Omran Abu Aboud, Ching‐Hsien Chen, William Senapedis et al. · Molecular Cancer Therapeutics · 2016 · 139 citations · Full text

Chemoprevention Strategy, Rcc Growth, Immunology +17