K Shimomura

TRANSCRIPTIONAL INHIBITION OF INSULIN BY FK506 AND POSSIBLE INVOLVEMENT OF FK506 BINDING PROTEIN-12 IN PANCREATIC β-CELL

K. Nakamura, K. Ohara, K Shimomura · Transplantation · 1995 · 175 citations

Immunology, Pancreas Transplantation, Glucagon Content +20

Growth hormone (GH) secretion from human lymphocytes is up-regulated by GH, but not affected by insulin-like growth factor-I.

Nobutaka Hattori, K Shimomura, Takashi Ishihara et al. · The Journal of Clinical Endocrinology & Metabolism · 1993 · 30 citations

Sensitive Enzyme, Human Growth, Immunology +17

Antiestrogenic and antitumor effects of droloxifene in experimental breast carcinoma.

Ikuo Kawamura, T Mizota, Sueo Mukumoto et al. · PubMed · 1989 · 18 citations

Breast Oncology, Gynecology, Pharmacotherapy +18

Possible involvement of calpain in the growth of estrogen receptor positive breast cancer cells.

Eiichi Shiba, Shoshin Kim, Masanori Fujitani et al. · PubMed · 1996 · 18 citations

Possible Involvement, Breast Oncology, Signal Transduction +15

Inhibition of insulin production by FK 506 is caused at the transcriptional level in pancreatic beta cell when FK BP-12 content is relatively high.

Kazuo Tamura, Takao Fujimura, Taiki Tsutsumi et al. · PubMed · 1995 · 10 citations

Insulin Production, Transcriptional Regulation, Signal Transduction +14