Jonathan Howe

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 173 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies

Mike O’Donovan, Marlies De Boeck, Dominique Brault et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2010 · 110 citations

Pharmacy, Pharmacology, Toxicology +11

Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing

Masamitu Honma, Andreas Czich, Marilyn J. Aardema et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2010 · 106 citations

Pharmacy, Toxicology, Molecular Toxicology +8

Are all bacterial strains required by OECD mutagenicity test guideline TG471 needed?

Richard V. Williams, David M. DeMarini, Leon F. Stankowski et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2019 · 56 citations · Full text

Pharmacy, Microbiology, Toxicology +15

N-Nitrosodimethylamine investigations in Muta™Mouse define point-of-departure values and demonstrate less-than-additive somatic mutant frequency accumulations

Anthony M Lynch, Jonathan Howe, Deon Hildebrand et al. · Mutagenesis · 2024 · 20 citations · Full text

Pharmacy, Pharmacology, Toxicology +15