Xin Huang

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial

Michael Wang, Simon Rule, Pier Luigi Zinzani et al. · The Lancet · 2017 · 448 citations · Full text

Medicine, Oncology, Pharmacotherapy +11

Novel Pyrazolo[4,3-<i>d</i>]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model

Jing Bo Shi, Liu Zeng Chen, Bao Shi Wang et al. · Journal of Medicinal Chemistry · 2019 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and antibacterial activities of novel pleuromutilin derivatives with a substituted pyrimidine moiety

Yunpeng Yi, Ximing Xu, Yu Liu et al. · European Journal of Medicinal Chemistry · 2016 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Design and synthesis of novel pyrazolo[4,3- <i>d</i> ]pyrimidines as potential therapeutic agents for acute lung injury

Bao Shi Wang, Xin Huang, Liu Zeng Chen et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2019 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant <scp><i>Btk</i>^<i>C481S</i></scp> mutation in B‐cell malignancies

Fu Gui, Jie Jiang, Zhixiang He et al. · British Journal of Pharmacology · 2019 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17