Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

Tim Forshew, Muhammed Murtaza, Christine Parkinson, +12

Science Translational Medicine

Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin

Christine C. Hudson, Mei Liu, Gary G. Chiang, +5

Molecular and Cellular Biology

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

Blue B. Lake, Rizi Ai, Gwendolyn E. Kaeser, +18

Science

Loss of <i>PTEN</i> facilitates HIF-1-mediated gene expression

Wayne Zundel, Cornelia Schindler, Daphne A. Haas‐Kogan, +9

Genes & Development

Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

Jean Fan, Neeraj Salathia, Rui Liu, +8

Nature Methods

Systems BiologyFunctional GenomicsNatural SciencesGeneticsOverdispersion Analysis +9

Quantitative phenotyping via deep barcode sequencing

Andrew Smith, Lawrence E. Heisler, Joseph Mellor, +6

Genome Research

PhenomicsFunctional GenomicsYeast Deletion CollectionEngineeringGenetics +13

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

E. Fragouli, Katharina Späth, S. Alfarawati, +7

PLoS Genetics

Connective Tissue Growth Factor–Specific Monoclonal Antibody Therapy Inhibits Pancreatic Tumor Growth and Metastasis

Nadja Dornhöfer, Suzanne Spong, Kevin L. Bennewith, +13

Cancer Research

Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment

Ioanna Papandreou, C. H. Ravi Krishna, Fiona Kaper, +3

Cancer Research

Identification of fifteen novel mutations in the tissue-nonspecific alkaline phosphatase (TNSALP) gene in European patients with severe hypophosphatasia

Étienne Mornet, A. Taillandier, S Peyramaure, +15

European Journal of Human Genetics

BiologyGenetic DisorderGeneticsPathogenesisInherited Metabolic Disease +7