Prediction of the Plasma Concentration Profiles of Orally Administered Drugs in Rats on the Basis of Gastrointestinal Transit Kinetics and Absorbability

Taiji Sawamoto, Shunji Haruta, Yuji Kurosaki, +2

Journal of Pharmacy and Pharmacology

Absorption ProfilesGastrointestinal PharmacologyGastroenterologyPlasma Concentration ProfilesDigestive Tract +16

An Effective Absorption Behavior of Insulin for Diabetic Treatment Following Intranasal Delivery Using Porous Spherical Calcium Carbonate in Monkeys and Healthy Human Volunteers

Shunji Haruta, Takashi Hanafusa, Hiroyuki Fukase, +2

Diabetes Technology & Therapeutics

Effective nose-to-brain drug delivery using a combination system targeting the olfactory region in monkeys

Keita Sasaki, Shota Fukakusa, Yusuke Torikai, +6

Journal of Controlled Release

Evaluation of absorption kinetics of orally administered theophylline in rats based on gastrointestinal transit monitoring by gamma scintigraphy

Shunji Haruta, Keiichi Kawai, Seishi Jinnouchi, +5

Journal of Pharmaceutical Sciences

Gastrointestinal PharmacologyMedicinePhysiologyGastroenterologyGastrointestinal Transit Monitoring +7

Absorption Behavior of Orally Administered Drugs in Rats Treated with Propantheline

Shunji Haruta, Norio Iwasaki, Ken‐ichi Ogawara, +2

Journal of Pharmaceutical Sciences

Analysis and prediction of absorption behavior of colon-targeted prodrug in rats by GI-transit-absorption model

Jun-ichi Yokoe, Norio Iwasaki, Shunji Haruta, +4

Journal of Controlled Release

MedicineAbsorption BehaviorPhysiologyGastroenterologyGi-transit-absorption Model +8

Prediction of plasma concentration–time curve of orally administered theophylline based on a scintigraphic monitoring of gastrointestinal transit in human volunteers

Shunji Haruta, Keiichi Kawai, Ryuichi Nishii, +6

International Journal of Pharmaceutics

Therapeutic Drug MonitoringGastrointestinal PharmacologyHuman VolunteersPharmacologyGastroenterology +9

Analysis and Prediction of Absorption Profile Including Hepatic First-Pass Metabolism of N-Methyltyramine, A Potent Stimulant of Gastrin Release Present in Beer, after Oral Ingestion in Rats by Gastrointestinal-Transit-Absorption Model

Toshikiro Kimura, Norio Iwasaki, J YOKOE, +4

Drug Metabolism and Disposition

Rapid Absorption of Dry-Powder Intranasal Oxytocin

Mikolaj Milewski, Adrian P. Goodey, Dinah Lee, +5

Pharmaceutical Research

Pharmaceutical ScienceMedicineRapid AbsorptionDrug AbsorptionPharmacology +1

Evaluation of Systemic and Mucosal Immune Responses Induced by a Nasal Powder Delivery System in Conjunction with an OVA Antigen in Cynomolgus Monkeys

Yusuke Torikai, Yuji C. Sasaki, Keita Sasaki, +3

Journal of Pharmaceutical Sciences

VaccinationAsthmaMucosal VaccinationAllergyCynomolgus Monkeys +10