Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle

Yukiko Okuno

The EMBO Journal

ChromatinChromatin AssociationChromatin StructureFunctional ActivityChromatin Remodeling +10

<i>In vitro</i> expansion of mouse primordial germ cell‐like cells recapitulates an epigenetic blank slate

Hiroshi Ohta, Kazuki Kurimoto, Ikuhiro Okamoto, +9

The EMBO Journal

Germ Cell BiologyChromatinEpigenetic Blank SlateEmbryonic Stem CellDevelopmental Biology +13

Clustered Adenine/Thymine Stretches Are Essential for Function of a Fission Yeast Replication Origin

Yukiko Okuno, Hiroyasu Satoh, Mariko Sekiguchi, +1

Molecular and Cellular Biology

GeneticsMolecular BiologyMolecular GeneticsCell CycleShort Adenine +15

Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia

Mayumi Yoshida, Naoyuki Kataoka, Kenjyo Miyauchi, +11

Proceedings of the National Academy of Sciences

Selective inhibition of the kinase DYRK1A by targeting its folding process

Isao Kii, Yuto Sumida, Toshiyasu Goto, +12

Nature Communications

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice

Akiko Nakano-Kobayashi, Tomonari Awaya, Isao Kii, +7

Proceedings of the National Academy of Sciences

The Chinese Hamster Dihydrofolate Reductase Replication Origin Decision Point Follows Activation of Transcription and Suppresses Initiation of Replication within Transcription Units

Takayo Sasaki, Sunita Ramanathan, Yukiko Okuno, +3

Molecular and Cellular Biology

Developmental BiologyTranscription UnitsCell DivisionNatural SciencesGenetics +12

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice

Satoshi Morooka, Mitsuteru Hoshina, Isao Kii, +17

Molecular Pharmacology

The Kinase Inhibitor SFV785 Dislocates Dengue Virus Envelope Protein from the Replication Complex and Blocks Virus Assembly

Azlinda Anwar, Takamitsu Hosoya, Hiroshi Onogi, +6

PLoS ONE

Virus StructureViral ReplicationBlocks Virus AssemblyDengue VirusReplication Complex +11

RB Reversibly Inhibits DNA Replication via Two Temporally Distinct Mechanisms

Steven P. Angus, Christopher N. Mayhew, David A. Solomon, +6

Molecular and Cellular Biology

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsCell Cycle +16