Dexin Deng

Degrading FLT3-ITD protein by proteolysis targeting chimera (PROTAC)

Yong Chen, Xue Yuan, Minghai Tang et al. · Bioorganic Chemistry · 2021 · 49 citations

Life Sciences, Biochemistry, Molecular Biology +9

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases

Kongjun Liu, Dan Li, Wei Zheng et al. · Journal of Medicinal Chemistry · 2021 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Limiting Effects of RIP140 in Estrogen Signaling

Kristina A. White, Mark M. Yore, Dexin Deng et al. · Journal of Biological Chemistry · 2005 · 33 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Discovery of Potent and Selective Receptor-Interacting Serine/Threonine Protein Kinase 2 (RIPK2) Inhibitors for the Treatment of Inflammatory Bowel Diseases (IBDs)

Xue Yuan, Yong Chen, Minghai Tang et al. · Journal of Medicinal Chemistry · 2022 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

Kelly C Heim, Kristina A. White, Dexin Deng et al. · Molecular Cancer · 2007 · 29 citations · Full text

Life Sciences, Molecular Biology, Oncology +17