Claudia Ferrara

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

Ekkehard Mössner, Peter Brünker, Samuel Moser et al. · Blood · 2010 · 929 citations · Full text

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

Claudia Ferrara, Sandra Grau, Christiane Jäger et al. · Proceedings of the National Academy of Sciences · 2011 · 735 citations

Glycobiology, Immunology, Immunotherapeutics +20

Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

Tilman Schlothauer, Sylvia Herter, Claudia Ferrara et al. · Protein Engineering Design and Selection · 2016 · 388 citations · Full text

Immunology, Immune Regulation, Immunodominance +24

The Carbohydrate at FcγRIIIa Asn-162

Claudia Ferrara, Fiona Stuart, Peter Sondermann et al. · Journal of Biological Chemistry · 2005 · 344 citations · Full text

Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co‐expression of heterologous β1, 4‐<i>N</i>‐acetylglucosaminyltransferase III and Golgi α‐mannosidase II

Claudia Ferrara, Peter Brünker, Tobias Suter et al. · Biotechnology and Bioengineering · 2006 · 298 citations

Localization Domain, Glycobiology, Molecular Biology +18