Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation

Jaerak Chang, Seongju Lee, Craig Blackstone

Journal of Clinical Investigation

MitophagyLysosomal TubulationProtein SecretionGeneticsMolecular Biology +17

Cellular senescence: a promising strategy for cancer therapy

Seongju Lee, Jae‐Seon Lee

BMB Reports

Lifespan ExtensionTumor BiologyDevelopmental BiologyMedicineCellular Senescence +7

FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

Seongju Lee, Jaerak Chang, Craig Blackstone

Nature Communications

Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation

Jaerak Chang, Seongju Lee, Craig Blackstone

Proceedings of the National Academy of Sciences

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization

Kyeongmi Kim, Seongju Lee, Jaerak Chang, +1

Experimental Cell Research

Platform ProteinCentriolar LocalizationSignal TransductionNovel FunctionProtein Assembly +9

Contribution of Autophagy-Notch1-Mediated NLRP3 Inflammasome Activation to Chronic Inflammation and Fibrosis in Keloid Fibroblasts

Seongju Lee, Sun Kyeon Kim, Hyungsun Park, +6

International Journal of Molecular Sciences

Enhanced Notch SignalingImmunologyPathologyAutophagy ActivityInflammation +14

Selectively Impaired Endocannabinoid-Dependent Long-Term Depression in the Lateral Habenula in an Animal Model of Depression

Ho-Yong Park, Jeehae Rhee, Seongju Lee, +1

Cell Reports

Synaptic TransmissionNeurotransmitterPsychopharmacologyLateral HabenulaNeurotransmission +26

MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis

Seongju Lee, Jaerak Chang, Benoît Renvoisé, +3

Molecular Biology of the Cell

ImmunologyCell DeathMolecular BiologyImmunologic MechanismCytoskeleton +19

Identification of Cathepsin D as a Plasma Biomarker for Alzheimer’s Disease

Jae-Whan Kim, Soonyoung Jung, Youngbin Kim, +7

Cells

Cathepsin DImmunologyPathologyNeurochemical BiomarkersAlzheimer ’ +20

Inflammasome‐mediated Inflammation by Malassezia in human keratinocytes: A comparative analysis with different strains

Hye-Ree Park, Jee Hye Oh, Yu Jin Lee, +5

Mycoses

Malassezia SpeciesMicrobial PathogensImmunologyImmune RegulationSkin Allergy +19