Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients

Kei Kawana, Katsuyuki Adachi, Satoko Kojima, +12

Vaccine

VaccinationE7-specific Mucosal ImmunityMucosal VaccinationOral VaccinationCancer-associated Virus +8

Matrix Metalloproteinase (MMP)-9 in Cancer-Associated Fibroblasts (CAFs) Is Suppressed by Omega-3 Polyunsaturated Fatty Acids In Vitro and In Vivo

Ayumi Taguchi, Kei Kawana, Kensuke Tomio, +17

PLoS ONE

PathologyCancer-associated FibroblastsCancer BiologyTumor BiologyFatty Acids +16

Resveratrol suppresses inflammatory responses in endometrial stromal cells derived from endometriosis: A possible role of the sirtuin 1 pathway

Ayumi Taguchi, Osamu Wada‐Hiraike, Kei Kawana, +7

Journal of obstetrics and gynaecology research

Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, +15

Oncotarget

Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor

Tomoko Inoue, Katsuyuki Adachi, Kei Kawana, +15

International Journal of Oncology

Chemoprevention StrategyImmunologyPvr ExpressionCell DeathNk Cells +14

Omega-3 Polyunsaturated Fatty Acids Suppress the Cystic Lesion Formation of Peritoneal Endometriosis in Transgenic Mouse Models

Kensuke Tomio, Kei Kawana, Ayumi Taguchi, +15

PLoS ONE

Peritoneal EndometriosisTransgenic Mouse ModelsLipid PeroxidationPathologyGynecology +15

Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes

Haruka Nishida, Yōko Matsumoto, Kei Kawana, +26

Journal of Controlled Release

NanomedicineEngineeringPolymer-drug ConjugateImmunologyVirology +6

Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth

Aki Yamashita, Kei Kawana, Kensuke Tomio, +18

Scientific Reports

The Prevalence Of Cervical Regulatory T Cells in HPV‐Related Cervical Intraepithelial Neoplasia (CIN) Correlates Inversely with Spontaneous Regression of CIN

Satoko Kojima, Kei Kawana, Kensuke Tomio, +15

American Journal of Reproductive Immunology

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

Asaha Fujimoto, Kei Kawana, Ayumi Taguchi, +16

Oncotarget

ApoptosisCell DeathCancer BiologyCancer Stem-like CellsTumor Biology +18