Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

Christine G. Lian, Yufei Xu, Craig J. Ceol, +27

Cell

ChromatinPhotocarcinogenesisMelanomaEpigenetic HallmarkMedicine +4

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

Yufei Xu, Chao Xu, Akiko Kato, +23

Cell

Xenopus EyeSignal TransductionDevelopmental BiologySignaling PathwayMolecular Regulation +10

Continuous Zebularine Treatment Effectively Sustains Demethylation in Human Bladder Cancer Cells

Jonathan Cheng, Daniel J. Weisenberger, Felicidad A. Gonzales, +5

Molecular and Cellular Biology

Histone ModificationsEpigenetic ChangeDna MethylationEpigeneticsOncology +15

RIM-BP3 is a manchette-associated protein essential for spermiogenesis

Jing Zhou, Yarui Du, Weihua Qin, +6

Development

SpermatogenesisDevelopmental BiologyMedicineGeneticsGamete +13

Superenhancer reprogramming drives a B-cell–epithelial transition and high-risk leukemia

Yeguang Hu, Zhihong Zhang, Mariko Kashiwagi, +11

Genes & Development

HDAC Inhibitors Act with 5-aza-2′-Deoxycytidine to Inhibit Cell Proliferation by Suppressing Removal of Incorporated Abases in Lung Cancer Cells

Guolin Chai, Lian Li, Wen Zhou, +13

PLoS ONE

Histone ModificationsEpigenetic ChangeCell ProliferationHdac InhibitorEpigenetics +17

STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming

Zhaowei Chu, Lei Gu, Yeguang Hu, +22

Nature Communications

Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS

Yeguang Hu, Daniela Salgado Figueroa, Zhihong Zhang, +7

Cell

Genome OrganizationLineage-specific 3DMultiple ScalesNatural SciencesGenetics +11