Thomas P. Caruso

Synthesis and pharmacologic characterization of an alkylating analog chlornaltrexamine, of naltrexone with ultralong-lasting narcotic antagonist properties

Philip S. Portoghese, Dennis L. Larson, Jianbing Jiang et al. · Journal of Medicinal Chemistry · 1979 · 108 citations

6.beta.-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5.alpha.-epoxy-3,14-dihydroxymorphinan (chloranaltrexamine), a potent opioid receptor alkylating agent with ultralong narcotic antagonist activity

Philip S. Portoghese, Dennis L. Larson, Jianbing Jiang et al. · Journal of Medicinal Chemistry · 1978 · 60 citations

Altmetric Attention Score, Pharmacotherapy, A. E. Takemori +16

Harnessing person-generated health data to accelerate patient-centered outcomes research: the Crohn’s and Colitis Foundation of America PCORnet Patient Powered Research Network (CCFA Partners)

Arlene E. Chung, Robert S. Sandler, Millie D. Long et al. · Journal of the American Medical Informatics Association · 2016 · 55 citations · Full text

Chloroxymorphamine, an Opioid Receptor Site-Directed Alkylating Agent Having Narcotic Agonist Activity

Thomas P. Caruso, A.E. Takemori, Dennis L. Larson et al. · Science · 1979 · 49 citations

Pharmacological studies with an alkylating narcotic agonist, chloroxymorphamine, and antagonist, chlornaltrexamine.

Thomas P. Caruso, Dennis L. Larson, Philip S. Portoghese et al. · Journal of Pharmacology and Experimental Therapeutics · 1980 · 39 citations