Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

Chul Hyoung Lyoo, Masamichi Ikawa, Jeih-San Liow, +6

Journal of Nuclear Medicine

¹¹C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain

Masamichi Ikawa, Talakad G. Lohith, Sanjay Telu, +7

Journal of Nuclear Medicine

Evaluation of striatal oxidative stress in patients with Parkinson's disease using [62Cu]ATSM PET

Masamichi Ikawa, Hidehiko Okazawa, Takashi Kudo, +3

Nuclear Medicine and Biology

MedicineNeurochemical BiomarkersNeuroprotectionNeurologyNeuroscience +3

PET imaging of redox and energy states in stroke-like episodes of MELAS

Masamichi Ikawa, Hidehiko Okazawa, Kenichiro Arakawa, +5

Mitochondrion

Positron Emission TomographyStroke-like EpisodesEnergy StatesMedical ImagingPet Imaging +11

Statins and Myotoxic Effects Associated With Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies

Yurika Watanabe, Shigeaki Suzuki, Hiroaki Nishimura, +9

Medicine

RheumatologyAutoimmune DiseaseMedicineImmunologyPathology +13

Radiolabeled Cu-ATSM as a novel indicator of overreduced intracellular state due to mitochondrial dysfunction: studies with mitochondrial DNA-less ρ0 cells and cybrids carrying MELAS mitochondrial DNA mutation

Yukie Yoshii, Makoto Yoneda, Masamichi Ikawa, +8

Nuclear Medicine and Biology

Genome InstabilityNovel IndicatorMitochondrial FunctionBiochemistryMitochondrial Dysfunction +11

Rho-kinase ROCK inhibitors reduce oligomeric tau protein

Tadanori Hamano, Norimichi Shirafuji, Shu‐Hui Yen, +8

Neurobiology of Aging

Protein FunctionProtein PhosphorylationMolecular BiologyOligomeric Tau Protein

Homocysteine Increases Tau Phosphorylation, Truncation and Oligomerization

Norimichi Shirafuji, Tadanori Hamano, Shu-Hui Yen, +7

International Journal of Molecular Sciences

Molecular BiologyNeurochemical BiomarkersOxidative StressAlzheimer's DiseaseDegenerative Pathology +22

Hashimoto’s Encephalopathy as a Treatable Adult-Onset Cerebellar Ataxia Mimicking Spinocerebellar Degeneration

Akiko Matsunaga, Masamichi Ikawa, Akihiro Fujii, +3

European Neurology

Detection of preclinically latent hyperperfusion due to stroke-like episodes by arterial spin-labeling perfusion MRI in MELAS patients

Masamichi Ikawa, Makoto Yoneda, Tomoko Muramatsu, +9

Mitochondrion

Melas PatientsStroke-like EpisodesVascular ImageLatent HyperperfusionMedical Imaging +13