Michael L. Gleghorn

Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity

Eonyoung Park, Michael L. Gleghorn, Lynne E. Maquat · Proceedings of the National Academy of Sciences · 2012 · 90 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay

Michael L. Gleghorn, Chenguang Gong, Clara L. Kielkopf et al. · Nature Structural & Molecular Biology · 2013 · 63 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Structural Basis for DNA-Hairpin Promoter Recognition by the Bacteriophage N4 Virion RNA Polymerase

Michael L. Gleghorn, Elena K. Davydova, Lucia B. Rothman‐Denes et al. · Molecular Cell · 2008 · 46 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides

Michael L. Gleghorn, Elena K. Davydova, Ritwika Basu et al. · Proceedings of the National Academy of Sciences · 2011 · 39 citations

Life Sciences, Biochemistry, Molecular Biology +17

Crystal structure of a poly(rA) staggered zipper at acidic pH: evidence that adenine N1 protonation mediates parallel double helix formation

Michael L. Gleghorn, Jianbo Zhao, Douglas H. Turner et al. · Nucleic Acids Research · 2016 · 30 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17