Mack Kuo

Inactivation of the <i>inhA</i> -Encoded Fatty Acid Synthase II (FASII) Enoyl-Acyl Carrier Protein Reductase Induces Accumulation of the FASI End Products and Cell Lysis of <i>Mycobacterium smegmatis</i>

Catherine Vilchèze, Héctor R. Morbidoni, Torin R. Weisbrod et al. · Journal of Bacteriology · 2000 · 278 citations

Targeting Tuberculosis and Malaria through Inhibition of Enoyl Reductase

Mack Kuo, Héctor R. Morbidoni, David Alland et al. · Journal of Biological Chemistry · 2003 · 258 citations · Full text

Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase

Remo Perozzo, Mack Kuo, Amar Bir Singh Sidhu et al. · Journal of Biological Chemistry · 2002 · 209 citations · Full text

Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4′-Substituted triclosan derivatives

Joel S. Freundlich, John W. Anderson, Dimitri Sarantakis et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 76 citations · Full text

Biological Activity, 4′-Substituted Triclosan Derivatives, Medicinal Chemistry +11

X-ray Structural Analysis of Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase as a Pathway toward the Optimization of Triclosan Antimalarial Efficacy

Joel S. Freundlich, Feng Wang, Han-Chun Tsai et al. · Journal of Biological Chemistry · 2007 · 73 citations · Full text

Biochemistry, Triclosan Antimalarial Efficacy, Medicine +13