Seppo Parkkila

HFE gene knockout produces mouse model of hereditary hemochromatosis

Xiao Zhou, Shunji Tomatsu, Robert E. Fleming et al. · Proceedings of the National Academy of Sciences · 1998 · 528 citations

Medicine, Genetics, Molecular Genetics +17

Experimental liver cirrhosis induced by alcohol and iron.

Hidekazu Tsukamoto, William C. Horne, Seiichiro Kamimura et al. · Journal of Clinical Investigation · 1995 · 521 citations · Full text

Medicine, Biochemistry, Toxicology +17

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

Vincenzo Alterio, Mika Hilvo, Anna Di Fiore et al. · Proceedings of the National Academy of Sciences · 2009 · 519 citations · Full text

Life Sciences, Biochemistry, Oncology +17

The Hemochromatosis Founder Mutation in HLA-H Disrupts β2-Microglobulin Interaction and Cell Surface Expression

John N. Feder, Zenta Tsuchihashi, Alivelu Irrinki et al. · Journal of Biological Chemistry · 1997 · 479 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β ₂ -microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

Abdül Waheed, Seppo Parkkila, Xiao Zhou et al. · Proceedings of the National Academy of Sciences · 1997 · 389 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17