A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis

Heiko Witt, Miklós Sahin‐Tóth, Olfert Landt, +60

Nature Genetics

Pancreatic CancerPancreatic Fluid CollectionImmunologyGastroenterologyPathology +3

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism

Éva Kereszturi, Richárd Szmola, Zoltán Kukor, +4

Human Mutation

Type TrypsinogenP.r116c TrypsinogenProtein SecretionGeneticsGastroenterology +17

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

Richárd Szmola, Zoltán Kukor, Miklós Sahin‐Tóth

Journal of Biological Chemistry

Presence of Cathepsin B in the Human Pancreatic Secretory Pathway and Its Role in Trypsinogen Activation during Hereditary Pancreatitis

Zoltán Kukor, Julia Mayerle, Burkhard Krüger, +5

Journal of Biological Chemistry

Human anionic trypsinogen

Zoltán Kukor, Miklós Tóth, Miklós Sahin‐Tóth

European Journal of Biochemistry

AllergyBiochemistryAfrican TrypanosomiasisMedicinePathogenesis +8

Human Cationic Trypsinogen

Zoltán Kukor, Miklós Tóth, Gábor Pál, +1

Journal of Biological Chemistry

Interaction between trypsinogen isoforms in genetically determined pancreatitis: Mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2)

Niels Teich, Cédric Le Maréchal, Zoltán Kukor, +8

Human Mutation

Anionic TrypsinogenGeneticsGastroenterologyPathologyMolecular Genetics +14

The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice*

Petra Pallagi, Zsolt Balla, Anurag Kumar Singh, +20

Critical Care Medicine

The Crucial Role of Early Mitochondrial Injury in L-Lysine-Induced Acute Pancreatitis

György Biczó, Péter Hegyi, Sándor Dósa, +15

Antioxidants and Redox Signaling

Expression of human cationic trypsinogen with an authentic N terminus using intein-mediated splicing in aminopeptidase P deficient Escherichia coli

Orsolya Király, Lan Guan, Edit Szepessy, +3

Protein Expression and Purification

Protein ExpressionVirulence FactorMolecular BiologyIntein-mediated SplicingMicrobiology +3