Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Ludwig Kappos, Amit Bar‐Or, Bruce Cree, +314

The Lancet

Neurological DisorderClinical NeurologyClinical TrialsSiponimod Versus PlaceboNeurological Monitoring +7

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Yuji Nagai, Naohisa Miyakawa, Hiroyuki Takuwa, +28

Nature Neuroscience

Behavioral ModulationsBehavioral NeuroscienceMedicineBehavioural PharmacologyPhysiology +11

Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

Tomonori Kaifu, Jin Nakahara, Masanori Inui, +15

Journal of Clinical Investigation

SclerostinImmune SystemOsteoporosisBone Morphogenic ProteinDegenerative Pathology +14

Clinical features and prognosis in anti-SRP and anti-HMGCR necrotising myopathy

Yurika Watanabe, Akinori Uruha, Shigeaki Suzuki, +5

Journal of Neurology Neurosurgery & Psychiatry

Inflammatory myopathy with anti-signal recognition particle antibodies: case series of 100 patients

Shigeaki Suzuki, Atsuko Nishikawa, Masataka Kuwana, +6

Orphanet Journal of Rare Diseases

Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study

James F. Howard, Saskia Bresch, Angela Genge, +184

The Lancet Neurology

MedicineSurgeryClinical TrialsGeneralised Myasthenia Gravis

Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial

Sonoko Misawa, Satoshi Kuwabara, Yasunori Sato, +76

The Lancet Neurology

MedicineNeurologyGuillain-barré SyndromePhase 2

Skeletal Muscle Involvement in Antisynthetase Syndrome

Eri Noguchi, Akinori Uruha, Shigeaki Suzuki, +8

JAMA Neurology

Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligodendrocyte precursor cells in multiple sclerosis

Jin Nakahara, Kohsuke Kanekura, Mikiro Nawa, +2

Journal of Clinical Investigation

Demyelinated AxonsNeurological DisorderNeurological ProgressCytoskeletonCellular Physiology +16

Inflammatory myopathy associated with PD-1 inhibitors

Morinobu Seki, Akinori Uruha, Yuko Ohnuki, +19

Journal of Autoimmunity

InflammationRheumatologyRheumatoid DisorderAutoimmune DiseaseRheumatic Diseases +5