Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer

Francesca De Bacco, Paolo Luraghi, Enzo Médico, +6

JNCI Journal of the National Cancer Institute

MET Signaling in Colon Cancer Stem-like Cells Blunts the Therapeutic Response to EGFR Inhibitors

Paolo Luraghi, Gigliola Reato, Élia Cipriano, +12

Cancer Research

Biological MicroenvironmentsPathologyTherapeutic ResponseEgfr InhibitorsTumor Biology +14

The <i>MET</i> Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype

Francesca De Bacco, Elena Casanova, Enzo Médico, +13

Cancer Research

Functional MarkerHigh-grade GliomasCancer BiologyGliomaTumor Biology +20

<scp>MET</scp> inhibition overcomes radiation resistance of glioblastoma stem‐like cells

Francesca De Bacco, Antonio D’Ambrosio, Elena Casanova, +15

EMBO Molecular Medicine

Poised Transcription Factories Prime Silent uPA Gene Prior to Activation

Carmelo Ferrai, Sheila Q. Xie, Paolo Luraghi, +5

PLoS Biology

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype

Barbara Lupo, Francesco Sassi, Marika Pinnelli, +29

Science Translational Medicine

Tumor BiologyGastrointestinal OncologyPi3k SignalingMedicineMaximal Response +12

LBA28 The PEGASUS trial: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients

Sara Lonardi, Filippo Pietrantonio, N. Tarazona Llavero, +17

Annals of Oncology

Surgical OncologyGastrointestinal OncologyColorectal SurgeryMedicineGastroenterology +9

The PEGASUS trial: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients.

Sara Lonardi, Clara Montagut, Filippo Pietrantonio, +16

Journal of Clinical Oncology

Ctdna+ PatientsSurgical OncologyColorectal SurgeryCancer ManagementGastroenterology +19

A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem–Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy

Paolo Luraghi, Viola Bigatto, Élia Cipriano, +11

Clinical Cancer Research

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

Valeria Leuci, Federica Maione, Ramona Rotolo, +15

Journal of Translational Medicine