Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Diego Adhemar Jaitin, Lorenz Adlung, Christoph A. Thaiss, +20

Cell

InflammationMetabolic SyndromePhysiologyAutophagyImmunology +6

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

Svetoslav Chakarov, Hwee Ying Lim, Leonard Tan, +28

Science

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

Zhaoyuan Liu, Yaqi Gu, Svetoslav Chakarov, +14

Cell

Cell LineageMedicineFate MappingCell Fate DeterminationSingle-cell Analysis +1

Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma

Ankur Sharma, Justine Jia Wen Seow, Charles‐Antoine Dutertre, +21

Cell

Endothelial CellsHepatocellular CarcinomaMedicineImmunologyLiver Cancer +6

Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

Kevin Mulder, Amit A. Patel, Wan Ting Kong, +29

Immunity

InflammationHuman CellCross-tissue Single-cell LandscapeGranulocyteMedicine +8

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

Camille Blériot, Théo Dupuis, Grégory Jouvion, +3

Immunity

InflammationHost ResponseBacterial InfectionsHepatologyBacterial Infection +12

Deterministic reprogramming of neutrophils within tumors

Melissa Ng, Immanuel Kwok, Leonard Tan, +39

Science

A subset of Kupffer cells regulates metabolism through the expression of CD36

Camille Blériot, Emelie Barreby, Garett Dunsmore, +41

Immunity

Signal TransductionMolecular PhysiologySignaling PathwayMolecular PathwayCell Regulation +8

Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming

Alexandre P. Bénéchet, Giorgia De Simone, Pietro Di Lucia, +25

Nature

Genomic LandscapeT-regulatory CellImmunologyAntigen ProcessingAutoimmunity +6

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling

Caleb A. Dawson, Bhupinder Pal, François Vaillant, +9

Nature Cell Biology

InflammationFibrosisMammary EpitheliumMammary GlandPathology +8