Matthew D. Pugh

Co(thd)2: a superior catalyst for aerobic epoxidation and hydroperoxysilylation of unactivated alkenes: application to the synthesis of spiro-1,2,4-trioxanes

Paul M. O’Neill, Stephen Hindley, Matthew D. Pugh et al. · Tetrahedron Letters · 2003 · 80 citations

Natural Sciences, Chemical Engineering, Chemistry +7

Design and Synthesis of Endoperoxide Antimalarial Prodrug Models

Paul M. O’Neill, Paul A. Stocks, Matthew D. Pugh et al. · Angewandte Chemie International Edition · 2004 · 60 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-en-1-ols: application to a new synthesis of 1,2,4-trioxanes

Paul M. O’Neill, Matthew D. Pugh, Jill Davies et al. · Tetrahedron Letters · 2001 · 57 citations

Natural Sciences, Chemistry, Catalysis +5

Optimisation of the allylsilane approach to C-10 deoxo carba analogues of dihydroartemisinin: synthesis and in vitro antimalarial activity of new, metabolically stable C-10 analogues

Paul M. O’Neill, Matthew D. Pugh, Andrew V. Stachulski et al. · Journal of the Chemical Society Perkin Transactions 1 · 2001 · 37 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Diels–Alder/thiol–olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore

Paul M. O’Neill, Edite Verissimo, Stephen A. Ward et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 19 citations

Medicine, Medicinal Chemistry, Pharmacology +8